Male circumcision: a new approach to reducing HIV transmission.

نویسنده

  • Stephen Moses
چکیده

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منابع مشابه

To cut or not to cut: a modeling approach for assessing the role of male circumcision in HIV control.

A recent randomized controlled trial shows a significant reduction in women-to-men transmission of HIV due to male circumcision. Such development calls for a rigorous mathematical study to ascertain the full impact of male circumcision in reducing HIV burden, especially in resource-poor nations where access to anti-retroviral drugs is limited. First of all, this paper presents a compartmental m...

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HIV and circumcision: new factors to consider.

Kebaabetswe et al obviously believe the conventional wisdom that heterosexual sex is the major vector for the transmission/ reception of HIV, and that male circumcision is an effective deterrent to infection. Based on that belief, they have constructed an elaborate and impressive study of the acceptability of circumcision as a prophylactic measure in Botswana. Furthermore, they argue for a prog...

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HIV and circumcision: new factors to consider

Kebaabetswe et al obviously believe the conventional wisdom that heterosexual sex is the major vector for the transmission/ reception of HIV, and that male circumcision is an effective deterrent to infection. Based on that belief, they have constructed an elaborate and impressive study of the acceptability of circumcision as a prophylactic measure in Botswana. Furthermore, they argue for a prog...

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Sub-Saharan African randomised clinical trials into male circumcision and HIV transmission: methodological, ethical and legal concerns.

In 2007, WHO/UNAIDS recommended male circumcision as an HIV-preventive measure based on three sub-Saharan African randomised clinical trials (RCTs) into female-to-male sexual transmission. A related RCT investigated male-to-female transmission. However, the trials were compromised by inadequate equipoise; selection bias; inadequate blinding; problematic randomisation; trials stopped early with ...

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Will circumcision provide even more protection from HIV to women and men? New estimates of the population impact of circumcision interventions

BACKGROUND Mathematical modelling has indicated that expansion of male circumcision services in high HIV prevalence settings can substantially reduce population-level HIV transmission. However, these projections need revision to incorporate new data on the effect of male circumcision on the risk of acquiring and transmitting HIV. METHODS Recent data on the effect of male circumcision during w...

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عنوان ژورنال:
  • CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

دوره 181 8  شماره 

صفحات  -

تاریخ انتشار 2009